Sure, the Closed Spanish, Open Spanish and Berlin have all been popular at times in the last 30 years, but don't forget about another solid variation against the Lopez: the Steinitz Defense. Players looking for a solid structure with a minimal space disadvantage might just catch their opponents by surprise with 3...d6. Today GM Dzindzichashvili focuses on 4. d4 and both possible recaptures. If it is good enough for a preeminent theoretician, it it surely good enough for you!