...Is 1.e5 out of favor?...
You mean 1. e4? 1. e5 is impossible for white
1.e4 has been much more extensively analysed than 1.d4. Ruy Lopez and Sicilian Defense have been analysed for more than 20 moves. You cannot surprise the opponent easily in openings so extensively analysed. But maybe the more important reason is, I think, 1.d4 is more favored by both Anand and Kramnik?
It appears that all six games in the World Chess Championship have begun with 1.d4. Why is 1.d4 so popular? Is 1.e5 out of favor? What about other opening moves?